English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Summary  The effect of cytochalasin B on hexose transport into rat pancreatic islets isolated by collagenase digestion has been investigated. A double radioactive label procedure has permitted correction for label present in the extracellular space and determined that the permeability of the B-cell membrane of collagenase treated islets to L-glucose and sucrose is insignificant under the conditions employed. Cytochalasin B (15 μg/ml) significantly inhibits the initial rate of uptake of D-glucose, 3-0-methyl-D-glucose, and 2-deoxy-D-glucose at temperature of 20°C and 37°C when islets are pre-incubated (20 min) in the presence of cytochalasin B. No significant inhibition is observed on the initial rate of uptake of D-glucose at a temperature of 37°C if cytochalasin B is present only in the incubation medium. The production of14CO2 from uniformly14C labeled D-glucose is unaltered in the presence of cytochalasin B over a 2 h incubation period.

Effect of cytochalasin B on hexose transport and glucose metabolism in pancreatic islets