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* Support for this work was provided by the National Library of Medicine under Grant LM-03395, and by the Office of Naval Research under contract NR 049-479. Computing facilities were provided by the SUMEXAIM resource under NIH Grant RR-00785. I also thank Ted Shortliffe and Bruce Buchanan for helpful comments on earlier drafts of this paper. t Heuristic Programming Project, Departments of Medicine and Computer Science, Stanford University, Stanford, California 94305.

Computer programs that adjust insulin dosage for diabetics who monitor their blood glucose