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Summary The diagnostic ultrasound was given to 21 healthy pregnant women who were undergoing induced abortion, and sister chromatid exchange (SCE) was analyzed on amniotic fluid cells before and after the ultrasonic exposure. There was no linear relationship between the SCE frequency and time of ultrasonic exposure. The SCE frequency was not significantly increased after the exposure as compared with that before the exposure. The data suggest that diagnostic ultrasound is a safe procedure when used for prenatal diagnosis.

Effects of diagnostic ultrasound on sister chromatid exchange frequencies of the amniotic fluid cells of the pregnant women