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Summary Quantitation of C3 and C3 proactivator in a healthy Indian population shows lower levels than in European populations, whereas the levels of all immunoglobulins except IgA are elevated. It is suggested that for the Indian subcontinent the normal IgE level should be taken as 400–500 iu/ml, a figure considerably higher than that in Europe. To assess the possibility of a genetic element in the regional serum protein variation, the association of the immunoglobulin and complement levels with several serum polymorphic characters is examined.

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Genetic polymorphism of serum proteins and levels of immunoglobulin and complement components in high caste community (Brahmins) of Madhya Pradesh, India