English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The study of tear film thickness and breakup has important implications for understanding tear physiology and dynamics. We have developed a complete end-to-end automated system for robust and accurate measurements of the tear film thickness from interferometric video as a function of position and time (following a blink). This paper will primarily address the problem of identifying dry regions on the surface of the contact lens, which is one of the four major components of the system. (The others are motion stabilization, image normalization, and phase demodulation to infer absolute thickness and map the surface. To address the challenging wet/dry segmentation problem, we propose a new Gaussian clustering method for feature extraction in high dimensional spaces. Each class is modeled as a mixture of Gaussians, clustered using Expectation-Maximization in the lower-dimensional Fisher's discriminant space. We show that this approach adapts to a wide range of distributions and is insensitive to training sample size. We present experimental results on the real-world problem of identifying regions of breakup (drying) of the prelens tear film from narrowband interferometry for contact lens wearers in vivo.

Resilient Subclass Discriminant Analysis with Application to Prelens Tear Film Interferometry