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We present a tool for simulation of populations of living cells interacting in spatial structures. Each cell is modelled with the Quasi-Steady Petri Net that integrates dynamic regulatory network expressed with a Petri Net (PN) and Genome Scale Metabolic Networks (GSMN) where linear programming is used to explore the steady-state metabolic flux distributions in the whole-cell model.

AB-QSSPN: Integration of Agent-Based Simulation of Cellular Populations with Quasi-Steady State Simulation of Genome Scale Intracellular Networks