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This research investigates the case of the Joint Programming Initiative (JPI) Urban Europe and its role as an intermediary organization, developing research, and innovation programs for urban transition. In the literature, the role of an intermediary organization has recently been discussed as an effective promoter and developer of connecting visions, strategies, activities, and stakeholders. A conceptual approach to intermediary organizations for urban transition is operationalized, and its functions are discussed in this paper. As an example, the Joint Programming Initiative Urban Europe reveals how a transnational R&amp;I initiative, represented by 20 national R&amp;I programs in Europe, can provide scientific evidence for sustainable urbanization with a cross-sectoral, integrated, inter- and transdisciplinary approach implemented through activities beyond joint calls. The findings show that JPI Urban Europe acts as broker and facilitator of joint visions and starts to build communities for innovation, which is one of the important functions of intermediaries. The development of its Strategic Research and Innovation Agenda clearly followed a co-creation process, putting the dilemmas of city practitioners in the center. JPI Urban Europe managed to attract high levels of commitment from a diversity of stakeholders to its strategic priorities and mobilized respective budgets for its implementation. The analysis of JPI Urban Europe participation in funded projects shows that challenge-driven calls (putting the problem owners in the center) seems to successfully develop a common language for all stakeholders and has a higher likelihood to generate more transformative outcomes. The number of funded urban living labs in projects shows that room for experimentation in niches and their extension is provided. The number of city representatives as funded project partners could be increased to further stimulate active involvement. The JPI Urban Europe also acts as a translator and enabler for learning in the urban—as well as in the policy sphere—the third function. This can be confirmed by the number and type of organizations reached with its specific formats. JPI Urban Europe coordinates joint activities of mainly national R&amp;I programs but has only indirect influence on change in these organizations and limited influence on changes within research organizations, businesses, or cities that are even less connected. Overall, it can be concluded that the strategic ambition of JPI Urban Europe towards transformative change is obvious, but some instruments and formats to translate the ambition into action need further refinement, and it needs further in-depth research to better understand the outcomes and impacts of its diverse activities.

City Engagement in the Joint Programming Initiative Urban Europe and the Role of Intermediary Organizations in R&I Policies for Urban Transition