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The London School of Economics (LSE) joins CERN as an established partner of the Future Circular Collider (FCC) Study, a project that touches many fields in and beyond physics. This volume coincides with the first steps of Horizon Europe in hopes of informing research and innovation planning. The challenges and scepticism facing Big Science were discussed but, despite them, we stand firm in support of the society-wide benefit of scientific projects of such magnitude. In concluding this volume, this article sums these perspectives, drawn from the joint CERN-LSE Alumni Association Belgium workshop held in 2019. Earlier, wider and greater benefits flow from Big, multi-disciplinary Science. These benefits are greatest when the core project is developed in open interaction with youth, local and global communities, engaging ecosystems capable of nurturing early spin-off innovation.

Epilogue: Productive Collisions—Blue-Sky Science and Today’s Innovations