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Voxel-based non-rigid registration algorithms have been successfully applied to a wide range of image types. However, in some cases the registration of quite different images, e.g. pre- and post-resection images, can fail because of a lack of voxel intensity correspondences. One solution is to introduce feature information into the voxel-based registration algorithms in order to incorporate higher level information about the expected deformation.We illustrate using one voxel-based registration algorithm that the incorporation of features yields considerable improvement of the registration results in such cases.

Using Points and Surfaces to Improve Voxel-Based Non-rigid Registration