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We analyzed the spatio-temporal patterns of the depth EEG recorded from a patient with lateral temporal-lobe epilepsy. Statistical analysis based on the Jensen-Shannon entropy (JS-E) as well as linear power spectral analyses were performed. The spatio-temporal patterns from JS-E and β rhythm successfully detected the onset timing of the seizure and revealed the temporal topology of the epileptic focus. The robustness of these patterns was proved by inter-trial consistency. As the patterns are well matched with the clinical diagnosis, it could be used for the identification of onset time and focus region of epileptic seizure.

Spatio-Temporal Patterns in the Depth EEG During the Epileptic Seizure