Open AccessBreast cancer diagnosis based on lipid profiling by probe electrospray ionization mass spectrometry
Author(s) -
Iwano T.,
Yoshimura K.,
Inoue S.,
Odate T.,
Ogata K.,
Funatsu S.,
Tanihata H.,
Kondo T.,
Ichikawa D.,
Takeda S.
Publication year - 2020
Publication title -
british journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.202
H-Index - 201
eISSN - 1365-2168
pISSN - 0007-1323
DOI - 10.1002/bjs.11613
Subject(s) - medicine , mass spectrometry , breast cancer , electrospray ionization , extractive electrospray ionization , profiling (computer programming) , ambient ionization , chromatography , cancer , ionization , protein mass spectrometry , chemical ionization , ion , chemistry , physics , quantum mechanics , computer science , operating system
Probe electrospray ionization mass spectrometry (PESI‐MS) is an ambient ionization‐based mass spectrometry method that surpasses the original electrospray ionization technique in features such as the rapidity of analysis, simplicity of the equipment and procedure, and lower cost. This study found that the PESI‐MS system with machine learning has the potential to establish a lipid‐based diagnosis of breast cancer with higher accuracy, using a simpler approach.Rapid mass spectrometry for breast cancer