Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level | Zendy

Kate Merritt | Zendy; Philip McGuire | Zendy; Alice Egerton | Zendy; H-MRS in Schizophrenia Investigators | Zendy; André Alemán | Zendy; Wolfgang Block | Zendy; Oswald Bloemen | Zendy; Faith Borgan | Zendy; Juan Bustillo | Zendy; Arístides A. Capizzano | Zendy; Jennifer M. Coughlin | Zendy; Camilo de la FuenteSandoval | Zendy; Arsime Demjaha | Zendy; Kara Dempster | Zendy; Kim Q. | Zendy; Fei Du | Zendy; Peter Falkai | Zendy; Beata Galińska-Skok | Zendy; Jürgen Gallinat | Zendy; Charles Gasparovic | Zendy; Cedric E. Ginestet | Zendy; Naoki Gotō | Zendy; Ariel GraffGuerrero | Zendy; BengChoon Ho | Zendy; Oliver Howes | Zendy; Sameer Jauhar | Zendy; Peter Jeon | Zendy; Tadafumi Kato | Zendy; Charles A. Kaufmann | Zendy; Lawrence S. Kegeles | Zendy; Matcheri S. Keshavan | Zendy; Sang-Young Kim | Zendy; Hiroshi Kunugi | Zendy; John Lauriello | Zendy; Edith J. Liemburg | Zendy; Meghan McIlwain | Zendy; Gemma Modinos | Zendy; Elias Mouchlianitis | Zendy; Jun Nakamura | Zendy; Igor Nenadić | Zendy; Döst Öngür | Zendy; Miho Ota | Zendy; Lena Palaniyappan | Zendy; Christos Pantelis | Zendy; Eric Plitman | Zendy; Sotirios Posporelis | Zendy; Scot E. Purdon | Zendy; Jürgen R. Reichenbach | Zendy; Perry F. Renshaw | Zendy; Bruce Russell | Zendy; Akira Sawa | Zendy; Martin Schaefer | Zendy; Dikoma C. Shungu | Zendy; Stefan Smesny | Zendy; Jeffrey A. Stanley | Zendy; James Stone | Zendy; Agata Szulc | Zendy; Reggie Taylor | Zendy; Katharine N. Thakkar | Zendy; Jean Théberge | Zendy; Philip G. Tibbo | Zendy; Thérèse van Amelsvoort | Zendy; Jerzy Walecki | Zendy; Peter Williamson | Zendy; Stephen J. Wood | Zendy; Lijing Xin | Zendy; Hidenori Yamasue | Zendy

Open Access

Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level

Author(s) -

Kate Merritt,

Philip McGuire,

Alice Egerton,

H-MRS in Schizophrenia Investigators,

André Alemán,

Wolfgang Block,

Oswald Bloemen,

Faith Borgan,

Juan Bustillo,

Arístides A. Capizzano,

Jennifer M. Coughlin,

Camilo de la FuenteSandoval,

Arsime Demjaha,

Kara Dempster,

Kim Q.,

Fei Du,

Peter Falkai,

Beata Galińska-Skok,

Jürgen Gallinat,

Charles Gasparovic,

Cedric E. Ginestet,

Naoki Gotō,

Ariel GraffGuerrero,

BengChoon Ho,

Oliver Howes,

Sameer Jauhar,

Peter Jeon,

Tadafumi Kato,

Charles A. Kaufmann,

Lawrence S. Kegeles,

Matcheri S. Keshavan,

Sang-Young Kim,

Hiroshi Kunugi,

John Lauriello,

Edith J. Liemburg,

Meghan McIlwain,

Gemma Modinos,

Elias Mouchlianitis,

Jun Nakamura,

Igor Nenadić,

Döst Öngür,

Miho Ota,

Lena Palaniyappan,

Christos Pantelis,

Eric Plitman,

Sotirios Posporelis,

Scot E. Purdon,

Jürgen R. Reichenbach,

Perry F. Renshaw,

Bruce Russell,

Akira Sawa,

Martin Schaefer,

Dikoma C. Shungu,

Stefan Smesny,

Jeffrey A. Stanley,

James Stone,

Agata Szulc,

Reggie Taylor,

Katharine N. Thakkar,

Jean Théberge,

Philip G. Tibbo,

Thérèse van Amelsvoort,

Jerzy Walecki,

Peter Williamson,

Stephen J. Wood,

Lijing Xin,

Hidenori Yamasue

Publication year - 2021

Publication title -

jama psychiatry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.531

H-Index - 365

eISSN - 2168-6238

pISSN - 2168-622X

DOI - 10.1001/jamapsychiatry.2021.0380

Subject(s) - proton magnetic resonance , schizophrenia (object oriented programming) , glutamate receptor , antipsychotic , psychiatry , medicine , magnetic resonance imaging , psychosis , psychology , neuroscience , nuclear magnetic resonance , receptor , radiology , physics

Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered brain glutamatergic function may be associated with the pathophysiology of schizophrenia and the response to antipsychotic treatment. However, the association of altered glutamatergic function with clinical and demographic factors is unclear.

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