Open AccessAnalysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer
Author(s) -
Thomas Reinert,
Tenna Vesterman Henriksen,
Emil Christensen,
Shruti Sharma,
Raheleh Salari,
Himanshu Sethi,
Michael Knudsen,
Iver Nordentoft,
Hsin-Ta Wu,
Antony Tin,
Mads H. Rasmussen,
Søren Vang,
Svetlana Shchegrova,
Amanda Frydendahl,
Ramya Srinivasan,
Zoe J. Assaf,
Mustafa Balcioglu,
Alexander Olson,
Scott Dashner,
Dina Hafez,
Samantha Navarro,
Shruti Goel,
Matthew Rabinowitz,
Paul R. Billings,
Styrmir Sigurjonsson,
Lars Dyrskjøt,
Ryan Swenerton,
Alexey Aleshin,
Søren Laurberg,
Anders Husted Madsen,
Anne-Sofie Kannerup,
Katrine Stribolt,
Søren Palmelund Krag,
Lene Hjerrild Iversen,
Kåre Andersson Gotschalck,
Cheng-Ho Jimmy Lin,
Bernhard Zimmermann,
Claus L. Andersen
Publication year - 2019
Publication title -
jama oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.846
H-Index - 99
eISSN - 2374-2445
pISSN - 2374-2437
DOI - 10.1001/jamaoncol.2019.0528
Subject(s) - medicine , colorectal cancer , oncology , cell free fetal dna , dna sequencing , dna , cancer , genetics , pregnancy , fetus , biology , prenatal diagnosis
Novel sensitive methods for detection and monitoring of residual disease can improve postoperative risk stratification with implications for patient selection for adjuvant chemotherapy (ACT), ACT duration, intensity of radiologic surveillance, and, ultimately, outcome for patients with colorectal cancer (CRC).
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