Open AccessAnalysis of Control Arm Quality in Randomized Clinical Trials Leading to Anticancer Drug Approval by the US Food and Drug Administration
Author(s) -
Talal Hilal,
Mohamad Bassam Sonbol,
Vinay Prasad
Publication year - 2019
Publication title -
jama oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.846
H-Index - 99
eISSN - 2374-2445
pISSN - 2374-2437
DOI - 10.1001/jamaoncol.2019.0167
Subject(s) - medicine , randomized controlled trial , food and drug administration , clinical endpoint , clinical trial , drug , surgery , pharmacology
To date, an empirical evaluation of the quality of control arms in randomized clinical trials (RCTs) leading to anticancer drug approvals by the US Food and Drug Administration (FDA) has not been undertaken.
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