Open AccessAssociation of Retinal Ganglion Cell Layer Thickness With Future Disease Activity in Patients With Clinically Isolated Syndrome
Author(s) -
Hanna Zimmermann,
Benjamin Knier,
Timm Oberwahrenbrock,
Janina Behrens,
Catherina Pfuhl,
Lilian Aly,
Miriam Kaminski,
MunaMiriam Hoshi,
Svenja Specovius,
René M. Gieß,
Michael Scheel,
Mark Mühlau,
Judith Bellmann–Strobl,
Klemens Ruprecht,
Bernhard Hemmer,
Thomas Korn,
Friedemann Paul,
Alexander U. Brandt
Publication year - 2018
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2018.1011
Subject(s) - medicine , interquartile range , clinically isolated syndrome , nerve fiber layer , optic neuritis , mcdonald criteria , magnetic resonance imaging , optic neuropathy , cohort , multiple sclerosis , ophthalmology , inner plexiform layer , retinal , optic nerve , radiology , psychiatry
Clinically isolated syndrome (CIS) describes a first clinical incident suggestive of multiple sclerosis (MS). Identifying patients with CIS who have a high risk of future disease activity and subsequent MS diagnosis is crucial for patient monitoring and the initiation of disease-modifying therapy.
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