Association of Treatment Intensity With Survival in Older Patients With Hodgkin Lymphoma

Key Points Question Is treatment with full, multiagent chemotherapy regimens associated with better survival compared with less-aggressive regimens in older adults with Hodgkin lymphoma? Findings In this population-based cohort study of 2686 patients aged 65 years or older with Hodgkin lymphoma, variability in the magnitude of the association between treatment intensity and mortality by stage and cause-specific mortality was found, possibly reflecting competing risks of death. However, full chemotherapy regimens tended to have the lowest mortality from any cause. Meaning These findings suggest that full, multiagent chemotherapy regimens may be associated with better survival in older adults who can tolerate them.