Open AccessOngoing Outbreak of Extensively Drug-ResistantCampylobacter jejuniInfections Associated With US Pet Store Puppies, 2016-2020
Author(s) -
Louise Francois Watkins,
Mark E. Laughlin,
Lavin A. Joseph,
Jessica C. Chen,
Megin Nichols,
Colin Basler,
Robert Breazu,
Christy Bennett,
Lia Koski,
Martha P. Montgomery,
Michael Hughes,
Scott Robertson,
Charlotte Lane,
Amber Singh,
Danielle Stanek,
Ellen Salehi,
Eric Brandt,
Glen McGillivary,
Jade Mowery,
Jamie DeMent,
Rachael D. Aubert,
Aimee Geissler,
Sietske de Fijter,
Ian T. Williams,
Cindy R. Friedman
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2021.25203
Subject(s) - multilocus sequence typing , outbreak , medicine , interquartile range , campylobacter jejuni , drug resistance , campylobacter , antibiotic resistance , antibiotics , biology , virology , microbiology and biotechnology , genotype , genetics , gene , bacteria
Key Points Question Are pet store puppies a source of extensively drug-resistant Campylobacter jejuni infection in the US? Findings This survey study identified 168 cases from public health reports of Campylobacter infections with an epidemiologic or molecular link to pet store puppies from 2011 to 2020; 97% of patients reported contact with a dog, of whom 88% reported contact with a pet store puppy. Isolates were resistant to 7 antibiotic classes, including all recommended treatment agents. Meaning Extensively drug-resistant C jejuni strains have emerged as a cause of illness among pet store customers, employees, and visitors; infections caused by these strains cannot be treated with commonly recommended oral antibiotics.
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