Open AccessTime to Clinical Benefit of Intensive Blood Pressure Lowering in Patients 60 Years and Older With Hypertension
Author(s) -
Tao Chen,
Fang Shao,
Kangyu Chen,
Yang Wang,
Zhenqiang Wu,
Yongjuan Wang,
Yanpei Gao,
Victoria Cornelius,
Chao Li,
Zhixin Jiang
Publication year - 2022
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2022.1657
Subject(s) - medicine , mace , blood pressure , clinical trial , stroke (engine) , randomized controlled trial , hazard ratio , myocardial infarction , adverse effect , cardiology , emergency medicine , physical therapy , percutaneous coronary intervention , confidence interval , engineering , mechanical engineering
Recent guidelines recommend a systolic blood pressure (BP) goal of less than 150 mm Hg or even 130 mm Hg for adults aged 60 years or older. However, harms from intensive BP treatments occur immediately (eg, syncope, fall), and benefits for cardiovascular event reduction emerge over time. Therefore, harms with low chance of benefit need to be clearer, particularly for those with limited life expectancy.
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