Open AccessStem Cell Mobilization by Granulocyte Colony-Stimulating Factor in Patients With Acute Myocardial Infarction<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>
Author(s) -
Dietlind Zohlnhöfer
Publication year - 2006
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.295.9.1003
Subject(s) - medicine , ejection fraction , myocardial infarction , granulocyte colony stimulating factor , cardiology , placebo , transplantation , clinical endpoint , surgery , randomized controlled trial , heart failure , pathology , chemotherapy , alternative medicine
Experimental studies and early phase clinical trials suggest that transplantation of blood-derived or bone marrow-derived stem cells may improve cardiac regeneration and neovascularization after acute myocardial infarction. Granulocyte colony-stimulating factor (G-CSF) induces mobilization of bone marrow stem cells.
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