Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure
Author(s) -
Alpha A. Fowler,
Jonathon D. Truwit,
R. Duncan Hite,
Peter E. Morris,
Christine DeWilde,
Anna Priday,
Bernard Fisher,
Leroy R. Thacker,
Ramesh Natarajan,
Donald F. Brophy,
Robin Sculthorpe,
Rahul Nanchal,
Aamer Syed,
Jamie Sturgill,
Greg S. Martin,
Jonathan Sevransky,
Markos Kashiouris,
Stella Hamman,
Katherine Egan,
Andrei Hastings,
Wendy Spencer,
Shawnda Tench,
Omar Mehkri,
James Bindas,
Abhijit Duggal,
Jeanette Graf,
Stephanie Zellner,
Lynda Yanny,
Catherine McPolin,
Tonya Hollrith,
David J. Kramer,
Charles I. Ojielo,
Tessa Damm,
Evan Cassity,
Aleksandra Wieliczko,
Matthew S. Halquist
Publication year - 2019
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2019.11825
Subject(s) - medicine , sepsis , ards , organ dysfunction , placebo , randomized controlled trial , systemic inflammation , intensive care , respiratory failure , septic shock , inflammation , anesthesia , lung , intensive care medicine , pathology , alternative medicine
Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS).
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