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Association of Oral Anticoagulants and Proton Pump Inhibitor Cotherapy With Hospitalization for Upper Gastrointestinal Tract Bleeding
Author(s) -
Wayne A. Ray,
Cecilia P. Chung,
Katherine T. Murray,
Walter Smalley,
James R. Daugherty,
William D. Dupont,
C. Michael Stein
Publication year - 2018
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2018.17242
Subject(s) - medicine , rivaroxaban , apixaban , dabigatran , incidence (geometry) , warfarin , cohort , gastrointestinal bleeding , cohort study , anticoagulant , proton pump inhibitor , retrospective cohort study , atrial fibrillation , surgery , gastroenterology , physics , optics
Anticoagulant choice and proton pump inhibitor (PPI) cotherapy could affect the risk of upper gastrointestinal tract bleeding, a frequent and potentially serious complication of oral anticoagulant treatment.

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