Open AccessDeterminants of Mother-to-Infant Human Immunodeficiency Virus 1 Transmission Before and After the Introduction of Zidovudine Prophylaxis
Author(s) -
Maurizio de Martino,
Luisa Galli,
Pier Angelo Tovo,
Clara Gabiano,
Patrizio Pezzotti,
Theresa Wagner,
Giovanni Rezza,
Patrizia Osimani,
Domenico De Mattia,
C. Di Bari,
Maurizio Ruggeri,
Federica Baldi,
M Ciccia,
Marcello Lanari,
Margherita De Masi,
Vanessa Venturi,
Luca Battisti,
Marzia Duse,
P. G. Chiriacò,
R Cavallini,
Carlo Dessì,
C. Pintor,
Elisa Anastasio,
Giuseppe Sabatino,
M Sticca,
Giulia Pomero,
T M Bezzi,
Elena Chiappini,
Marcello De Luca,
Paola Gervaso,
M Cecchi,
Dante Bassetti,
Cristina Gotta,
Raffaella Rosso,
Anna Timitilli,
U. Di Tondo,
P. Mussini,
Dorella Bricalli,
A. Bucceri,
G Ferraris,
M Giovannini,
Fabio Mosca,
Rita Lipreri,
A Plebani,
Enrica Riva,
Silvia Riva,
Alessandra Viganò,
Gianvincenzo Zuccotti,
Monica Cellini,
Wilma Buffolano,
Alfredo Guarino,
Léa Tarallo,
R D'Elia,
Carlo Giaquinto,
Osvalda Rampon,
Ernesto Renato Dalle Nogare,
Amelia Romano,
Desirée Caselli,
Anna Maccabruni,
Rita Consolini,
G Benaglia,
C. Magnani,
Gianfranco Anzidei,
Anna Maria Casadei Pistilli,
Guido Castelli Gattinara,
Salvatore Catania,
C. Facente,
P. Falconieri,
C. Fundarò,
Orazio Genovese,
C. Rendeli,
S. Bionda,
Letizia Cristiano,
Stefano Garetto,
C. Riva,
E Palomba,
V. Portelli,
Antonio Mazza,
Salvatore Casari,
A. Pellegatta,
M. Molesini
Publication year - 2002
Publication title -
archives of pediatrics and adolescent medicine
Language(s) - English
Resource type - Journals
eISSN - 1538-3628
pISSN - 1072-4710
DOI - 10.1001/archpedi.156.9.915
Subject(s) - medicine , zidovudine , transmission (telecommunications) , pediatrics , odds ratio , population , psychological intervention , breastfeeding , randomized controlled trial , observational study , human immunodeficiency virus (hiv) , immunology , surgery , viral disease , environmental health , psychiatry , electrical engineering , engineering
Randomized controlled trials have demonstrated that zidovudine therapy decreases the mother-to-infant transmission of human immunodeficiency virus 1 (HIV-1). Data from large observational studies may provide further important findings on the effectiveness at the population level of combined treatments in decreasing transmission.