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To test whether anti-CD3/anti-CD28 (alphaCD3/alphaCD28) monoclonal antibodies could be coated on surgical suture and used to enhance T-cell immune function in patients with advanced-stage head and neck squamous cell carcinoma (HNSCC).

Anti-CD3/Anti-CD28 Monoclonal Antibody–Coated Suture Enhances the Immune Response of Patients With Head and Neck Squamous Cell Carcinoma