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1. Stallard HB. Radiant energy as (a) pathogenic and (b) a therapeutic agent in ophthalmic disorders. Br J Ophthalmol. 1933;1:70. 2. Parsons JT, Bova FJ, Fitzgerald CR, Mendenhall WM, Million RR. Radiation retinopathy after external-beam irradiation: analysis of timedose factors. Int J Radiat Oncol Biol Phys. 1994; 30(4):765-773. 3. Haye C, Desjardins L, Bouder P, Schlienger P, Dorval T. Maculopathy caused by irradiation in patients treated for choroid melanoma. Ophtalmologie. 1990;4(3):229-231. 4. Finger PT, Chin KJ. Anti-vascular endothelial growth factor bevacizumab (Avastin) for radiation retinopathy. Arch Ophthalmol. 2007; 125(6):751-756. 5. Finger PT. Anti-VEGF bevacizumab (Avastin) for radiation optic neuropathy. Am J Ophthalmol. 2007;143(2):335-338. 6. Finger PT. Radiation retinopathy is treatable with anti-vascular endothelial growth factor bevacizumab (Avastin). Int J Radiat Oncol Biol Phys. 2008;70(4):974-977. 7. Wen JC, McCannel TA. Treatment of radiation retinopathy following plaque brachytherapy for choroidal melanoma. Curr Opin Ophthalmol. 2009;20(3):200-204. 8. Horgan N, Shields CL, Mashayekhi A, Shields JA. Classification and treatment of radiation maculopathy. Curr Opin Ophthalmol. 2010; 21(3):233-238. 9. Rosenfeld PJ, Schwartz SD, Blumenkranz MS, et al. Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular agerelated macular degeneration. Ophthalmology. 2005;112(6):1048-1053. 10. Ziemssen F, Voelker M, Altpeter E, BartzSchmidt KU, Gelisken F. Intravitreal bevacizumab treatment of radiation maculopathy due to brachytherapy in choroidal melanoma. Acta Ophthalmol Scand. 2007;85(5):579-580. 11. Loukianou E, Brouzas D, Georgopoulou E, Koutsandrea C, Apostolopoulos M. Intravitreal bevacizumab for macular edema due to proton beam radiotherapy: favorable results shown after eighteen months follow-up. Ther Clin Risk Manag. 2010;6:249-252. 12. Gupta A, Muecke JS. Treatment of radiation maculopathy with intravitreal injection of bevacizumab (Avastin). Retina. 2008;28(7): 964-968. 13. Mason JO III, Albert MA Jr, Persaud TO, Vail RS. Intravitreal bevacizumab treatment for radiation macular edema after plaque radiotherapy for choroidal melanoma. Retina. 2007; 27(7):903-907. 14. Eghøj MS, Sørensen TL. Tachyphylaxis during treatment of exudative age-related macular degeneration with ranibizumab. Br J Ophthalmol. 2012;96(1):21-23. 15. Forooghian F, Chew EY, Meyerle CB, Cukras C, Wong WT. Investigation of the role of neutralizing antibodies against bevacizumab as mediators of tachyphylaxis. Acta Ophthalmol. 2011; 89(2):e206-e207. 16. Schaal S, Kaplan HJ, Tezel TH. Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in agerelated macular degeneration? Ophthalmology. 2008;115(12):2199-2205. 17. Hoffman BB, Taylor P. Neurotransmission: the autonomic and somatic motor nervous systems. In: Goodman LS, Hardman JG, Limbird LE, Gilman AG, eds. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. 10th ed. New York, NY: McGraw-Hill; 2001:115-154. 18. Gasperini JL, Fawzi AA, Khondkaryan A, et al. Bevacizumab and ranibizumab tachyphylaxis in the treatment of choroidal neovascularisation. Br J Ophthalmol. 2012;96(1):14-20. 19. Finger PT, Chin KJ. Intravitreous ranibizumab (Lucentis) for radiation maculopathy. Arch Ophthalmol. 2010;128(2):249-252. 20. Yuan A, Singh RP. Radiation maculopathy treated with ranibizumab. J Clin Exp Ophthalmol. 2011; 2(2):1-4. doi:10.4172/2155-9570.1000129.

Bietti Crystalline Retinopathy: Report of Retinal Crystal Deposition in Male Adolescent Siblings