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Cosmetic alteration of the iris color has long intrigued individuals. This has been accomplished with cosmetic contact lenses and most recently with intraocular artificial iris implants. We report 2 cases of uveitis, glaucoma, and corneal decompensation in women who underwent bi la tera l s imultaneous implantation of a non–US Food and Drug Administration–approved cosmetic iris implant (NewColorIris). This device is a plate-styled colored silicone prosthesis designed for placement in the anterior chamber. Both patients had traveled to Panama City, Panama, to undergo the elective procedure. After surgery, both developed variants of an ocular complex comprising uveitis, glaucoma, and corneal decompensation and requiring explantation of the cosmetic iris implants. Various in situ and extirpated imaging techniques demonstrate implant placement, size, and surface characteristics that likely contributed to the ocular complications in these 2 cases.

Two Cases of Cosmetic Iris Implant Explantation Secondary to Uveitis, Glaucoma, and Corneal Decompensation