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further investigation, but this report provides evidence that iron overload can occur in AMD not only in the RPE and Bruch’s membrane but also in the neurosensory retina. Because iron can cause oxidative stress, it may be toxic to both the RPE and photoreceptors, cells in which cell death leads to blindness in AMD. Iron chelation therapy may one day prove useful in the prevention of vision loss due to AMD.

Optical Coherence Tomographic Findings of Combined Hamartoma of the Retina and Retinal Pigment Epithelium in 11 Patients