Systemic Anaplastic Large Cell Lymphoma Presenting With Conjunctival Involvement

Ocular and ocular adnexal lymphomas are uncommon and may have protean clinical presentations. They may be either primary neoplasms or secondary manifestations of systemic disease. The recognition of both nodal and extranodal lymphomas and the use of molecular biological techniques to delineate these entities have lead to diagnostically accurate and prognostically significant classification schemas. Anaplastic large cell lymphoma is a distinct entity recognized in the World Health Organization (WHO) classification of lymphomas. It is characterized by large cells with reniform nuclei and constant CD30 antibody expression. It may arise de novo or follow anaplastic transformation of another lymphoma. We report the fifth case of anaplastic large cell lymphoma involving the ocular adnexae.