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REPORT OF A CASE A 23-year-old woman presented with an 8-year history of progressive diffuse plane xanthomata of the face and neck. Beginning at the earlobes and neck, these yellow- ish maculopapular lesions had spread over the whole face and neck region, making the patient look as if she were wearing a mask (Figure 1A and Figure 2A). Histo- logic features were typical for plane xanthoma with mul- tiple foam cells surrounding the sebaceous glands and hair follicles in the whole dermis, in parts reaching the dermis-fat junction. Electron microscopic findings showed foamy histiocyte-like cells and solitary infiltrating giant cells in the dermis. Triglyceride, lipoprotein, and cho- lesterol levels were normal. Other reasons (eg, mono- clonal gammopathies, lymphoproliferative diseases, or normolipemic xanthomatous syndromes) were ex- cluded as well by findings from lipid- and immunoelec- trophoresis, blood cell counts, radiography of the skull, and electron microscopy, which were consistent with dif- fuse idiopathic plane xanthoma (group II, type 1). THERAPEUTIC CHALLENGE

Treatment of Diffuse Plane Xanthoma of the Face With the Erbium:YAG Laser