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The manipulation of geometrically constrained magnetic domain walls (DWs) innanoscale magnetic strips has attracted much interest recently, with proposalsfor prospective memory and logic devices. Here we propose to use the highcontrollability of the motion of geometrically constrained DWs for themanipulation of individual nanoparticles on a chip with an active control ofposition at the nanometer scale. The proposed method exploits the fact thatmagnetic nanoparticles in solution can be captured by a DW, whose position canbe manipulated with nanometric accuracy in a specifically designed magneticnanowire structure. We show that the high control over DW nucleation,displacement, and annihilation processes in such structures can be used tocapture, transport and release magnetic nanoparticles. As magnetic particleswith functionalized surfaces are commonly used as molecule labels in severalapplications - including single molecule manipulation, separation, cellsmanipulation and biomagnetic sensing, the accurate control over the handling ofthe single magnetic nanoparticles becomes crucial as it may reflect thehandling of the single molecules. The approach described here opens the path tothe implementation and design of nano-transport lines, with application tosingle molecule study and lab-on-chip devices. In perspective, the easyintegration on chip with sensors of domain walls and particles will allow forthe realization of programmable circuits for molecular manipulation withcontinuous control of the desired process.

On-chip nano-manipulation of magnetic particles via domain walls conduits