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Isochores are long genome segments relatively homogeneous in G+C. A heuristicalgorithm based on entropic segmentation has been developed by our group, and aweb server implementing all the required components is available. However, aresearcher may want to perform batch processing of many sequencessimultaneously in its local machine, instead of analyzing them on one by onebasis through the web. To this end, standalone versions are required. We reporthere the implementation of two standalone programs, able to predict isochoresat the sequence level: 1) a command-line version (IsoFinder) for Windows andLinux systems; and 2) a user-friendly version (IsoFinderWin) running underWindows.

A standalone version of IsoFinder for the computational prediction of isochores in genome sequences