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String instanton effects in Higgs physics are discussed through a type IIAmodel based on T^{6}/(Z^{2}\times Z^{'2}) orentifold compactifaction. Byinclusion of rigid E2-branes, the model exhibits a MSSM-like spectrum, as wellas extra mu and quartic Higgs couplings. These extra couplings are induced viaE2 instantons non-perturbatively. Setting the string scale at 10^{18} GeV, onegets interesting TeV Higgs physics. In particlular, the tree-level Higgs masscan be uplifted substantially.

E2 Instanton Effects and Higgs Physics In Intersecting Brane Models