English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Genomes evolve as modules. In prokaryotes (and some eukaryotes), geneticmaterial can be transferred between species and integrated into the genome viahomologous or illegitimate recombination. There is little reason to imaginethat the units of transfer correspond to entire genes; however, such units havenot been rigorously characterized. We examined fragmentary genetic transfers insingle-copy gene families from 144 prokaryotic genomes and found thatbreakpoints are located significantly closer to the boundaries of genomicregions that encode annotated structural domains of proteins than expected bychance, particularly when recombining sequences are more divergent. Thiscorrelation results from recombination events themselves and not fromdifferential nucleotide substitution. We report the first systematic studyrelating genetic recombination to structural features at the protein level.

Protein domains as units of genetic transfer