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The study of time lags between spikes in Gamma-Ray Bursts light curves indifferent energy bands as a function of redshift may lead to the detection ofeffects due to Quantum Gravity. We present an analysis of 15 Gamma-Ray Burstswith measured redshift, detected by the HETE-2 mission between 2001 and 2006 inorder to measure time lags related to astrophysical effects and search forQuantum Gravity signature in the framework of an extra-dimension string model.The use of photon-tagged data allows us to consider various energy ranges.Systematic effects due to selection and cuts are evaluated. No significantQuantum Gravity effect is detected from the study of the maxima of the lightcurves and a lower limit at 95% Confidence Level on the Quantum Gravity scaleparameter of 3.2x10**15 GeV is set.

Study of time lags in HETE-2 Gamma-Ray Bursts with redshift: search for astrophysical effects and Quantum Gravity signature