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The frequency distribution of DNA bases A, C, G, T exhibit fractalfluctuations ubiquitous to dynamical systems in nature. The power spectra offractal fluctuations exhibit inverse power law form signifying long-rangecorrelations between local (small-scale) and global (large-scale)perturbations. The author has developed a general systems theory based onclassical statistical physics for fractal fluctuations which predicts that theprobability distribution of eddy amplitudes and the variance (square of eddyamplitude)spectrum of fractal fluctuations follow the universal Boltzmanninverse power law expressed as a function of the golden mean. The modelpredicted distribution is very close to statistical normal distribution forfluctuations within two standard deviations from the mean and exhibits a fatlong tail. In this paper it is shown that DNA base CG frequency distribution inTakifugu rubripes (Puffer fish) Genome Release 4 exhibit universal inversepower law form consistent with model prediction. The observed long-rangecorrelations in the DNA bases implies that the non-coding 'junk' or 'selfish'DNA which appear to be redundant, may also contribute to the efficientfunctioning of the protein coding DNA, a result supported by recent studies.

Universal spectrum for DNA base CG frequency distribution in Takifugu rubripes (Puffer fish) genome