Open Access
Antibacterial Effect of Cinnamon Oil against Uropathogenic Multidrug Resistant
Author(s) -
Rana Thamer Hadi Alkhafaji,
M Jayashankar
Publication year - 2022
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2022/v34i33a36121
Subject(s) - microbiology and biotechnology , minimum inhibitory concentration , antimicrobial , minimum bactericidal concentration , staphylococcus aureus , agar diffusion test , essential oil , agar , multiple drug resistance , chemistry , antibiotics , biology , food science , bacteria , genetics
Cinnamon is known for its antimicrobial activity and the aim of this study was to investigate the effect of its essential oil against ten of the multidrug-resistant uropathogenic by agar well diffusion assays. The diameters of the inhibition zone to the Cinnamon oil were 27 mm for S. aureus, 24 mm for E coli, 20 mm for P.aeruginosa, 22 mm for K.pneumoniae, 23 mm for E.aerogenes & P. mirabilis, 24 mm for E. faecalis, and 27 mm for N.gonorrhoeae, A.baumanni, S.epidermis. In this study, the antimicrobial effects of the cinnamon essential oil are evaluated by determining the minimum inhibitory concentration (MIC), the inhibition zone, and minimum bactericidal concentration (MBC). Cinnamon was the most effective agent in inhibiting A.baumanni, N.gonorrhoeae, S. epidermis, E. faecalis and E. coli with the lowest MIC (0.0313%) while S.aureus, E. aerogenes and P. aeruginosa with MIC (0.125%) while P. mirabilis was 0.0625% in our study. The MBC was 0. 25% for A.baumanni, 0.5 % for N, gonorrhoeae, S. epidermis, E. faecalis, and K. pneumonia, while 1% S.aureus, E. aerogenes, P. mirabilis, E. coli, and P. aeruginosa.