Open AccessPavonia odorata Derived Phytochemicals against Entamoeba histolytica Causing Dysentery
Author(s) -
Jogesh Kumar Nayak,
Suraj Kumar Sahu,
Sitaram Swain,
Dipankar Bhattacharyay,
Mukundjee Pandey
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i830531
Subject(s) - entamoeba histolytica , dysentery , biology , palmitic acid , entamoeba , microbiology and biotechnology , traditional medicine , biochemistry , medicine , fatty acid
Phytochemicals from Pavonia odorata plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that palmitic acid can effectively deactivate the Alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.