Open AccessGuava Seeds Derived Phytochemicals against Dysentery
Author(s) -
Lopita Mishra,
Barsha Nayak,
Bibhu Prasad Mishra,
Dipankar Bhattacharya,
Mukundjee Pandey
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i730522
Subject(s) - entamoeba histolytica , biology , phytochemical , dysentery , microbiology and biotechnology , traditional medicine , biochemistry , medicine
Phytochemicals are the secondary metabolites that are known as nonnutritive but extremely beneficial for the defensive system for the organism. These phytochemicals can be obtained from all the plants and they play a major role in curing differnt diseases. The extract of the guava seed contains various phytochemicals that can cure the disease like dysentery, caused by the protozoa parasite, namely Entamoeba histolytica. “Biovia Discovery Studio” was used for the molecular docking process. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Heptadecanoic acid can effectively deactivate the alcohol dehydrogenase enzyme further inhibiting the biological process of the causative organism.