Open AccessCinnamomum zeylanicum (Cinnamon) Derived Phytochemicals against Aspartate Semialdehyde Dehydrogenase of Aspergillus fumigatus Causing Aspergillosis
Author(s) -
Biswajit Jena,
Minati Rani Muni,
P. K. Prusty,
Sunil Kumar Jha,
Deepankar Bhatttacharyay
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i730512
Subject(s) - aspergillus fumigatus , cinnamomum zeylanicum , aspergillosis , phytochemical , cinnamomum , biology , aspergillus , cinnamic acid , microbiology and biotechnology , traditional medicine , botany , medicine , biochemistry , pathology , essential oil , alternative medicine , traditional chinese medicine , cassia
Aspergillosis is an infection caused by a type of fungus. The illnesses is caused by aspergillosis infection and usually attack the respiratory system, but their signs and severity vary greatly. It has already been established that plant Cinnamomum zeylanicum belonging to the Lauraceae family has the potential to help controlling aspergillosis. This work is focused on the identification of the particular phytochemical responsible for inhibiting and decreasing the effect of aspergillosis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that cinnamic acid can effectively deactivate aspergillosis.