Open AccessPrevalence, Pattern and Monitoring of Adverse Drug Reaction in Tertiary Care Psychiatry Setting- A Hospital Based Study in South Kerala
Author(s) -
Dhanya Dharman,
S. Krishnan,
K. Ravikumar
Publication year - 2021
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i4231052
Subject(s) - pharmacovigilance , medicine , psychiatry , observational study , adverse effect , medical prescription , adverse drug reaction , risperidone , drug , incidence (geometry) , psychiatric hospital , schizophrenia (object oriented programming) , emergency medicine , pharmacology , physics , optics
Pharmacovigilance programs usually aim to gather information on the effect of prescribed drugs in the real world rather than in groups of short-lived and carefully selected clinical trial populations. Adverse drug reactions (ADR) associated with psychiatric medications may vary among different populations. As compared with other fields, in Kerala the research related to ADRs and Prescription patterns in psychiatry is scarce. A hospital based cross sectional observational study was undertaken in the Mental Health Centre, Trivandrum. All psychiatric drugs were closely monitor for adverse drug reaction irrespective of their psychiatric diagnosis. CDSCO Suspected adverse drug reaction reporting form was used for the documentation of adverse drug reaction and the causality assessment was done with naranjo scale .The severity of ADR was assessed using Hartwing scale and Preventability assessment using Modified schumock. In this study it was found the highest incident of ADR was reported with risperidone (24%) followed by valproate (20.1%), clozapine (17%) etc. The patient in psychiatry cant identify the adverse effect due to the cognitive impairment. So special attention is necessary for psychiatric patient to find out the incidence of adverse drug reaction and provide the proper management to them.