Open AccessComparison of Two Irrigation Solutions in the Surgical Removal of the Mandibular Third Molars- A Randomized Trial
Author(s) -
Prathibha Reddy,
P. U. Abdul Wahab,
V. Jagadish,
Preethika Murugan
Publication year - 2020
Publication title -
journal of pharmaceutical research international
Language(s) - English
Resource type - Journals
ISSN - 2456-9119
DOI - 10.9734/jpri/2020/v32i2830868
Subject(s) - medicine , metronidazole , molar , trismus , saline , osteitis , dentistry , dry socket , chlorhexidine , randomized controlled trial , therapeutic irrigation , randomization , surgery , anesthesia , osteomyelitis , microbiology and biotechnology , biology , antibiotics
Aim: To evaluate the effect of postoperative irrigation with chlorhexidine saline irrigation and metronidazole saline irrigation on non-inflammatory complications after the extraction of lower third molar under local anesthesia.
Materials and Methods: In this study a total of 120 patients with age range 18-80 years who had impacted tooth which required surgical removal were included. The patients were separated into two groups using Block Randomization to avoid sampling bias. Group A and Group B had 60 patients each. Group A patients were irrigated with 1% Chlorhexidine Saline and Group B patients were irrigated with 1% Metronidazole Saline during the surgical removal of their mandibular third molars. The patients were measured for the pain, swelling and checked for dry socket after 7 days of procedure.
Results: The mean age of the patient was 28.08 + SEM years. Out of three parameters (Pain, Swelling, Dry Socket) assessed, only alveolar osteitis showed a statistical significant difference between 1% Metronidazole and 1% Chlorhexidine with p value 0.041(>0.05). Trismus and pain did not differ significantly (p>0.05) in the two groups with p-values of 0.431 for trismus and 0.750 for pain.
Conclusion: Metronidazole had better efficacy in alveolar osteitis, while in the other parameters viz, pain and mouth opening there was no difference in the two treatments.