Open AccessImmuno-Histochemical and Quantitative Study of Melanocytes and Melanin Granules in Oral Epithelial Dysplasia
Author(s) -
Swapna Honwad
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/26096.10206
Subject(s) - melanin , melanocyte , epithelial dysplasia , dysplasia , h&e stain , pathology , magnification , immunohistochemistry , staining , melanoma , biology , medicine , cancer research , biochemistry , computer science , computer vision
Oral Epithelial dysplasia (OED) is a potentially malignant disorder that is characterized by the presence of architectural and cytological changes. One of the prime factors responsible for the development of these lesions is the usage of tobacco. A variety of factors provide protective mechanism in order to prevent the effects of chemotoxic agents including tobacco products of which, melanin pigmentation is one of the vital elements.