Open AccessMulticentric Metaplastic Breast Carcinoma with Squamous Differentiation
Author(s) -
Sunil Vitthalrao Jagtap,
Suresh Bhosale,
Pandurang G. Chougule,
S Dhawan,
Dhiraj Shukla
Publication year - 2015
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2015/12794.6218
Subject(s) - medicine , malignancy , immunohistochemistry , pathology , breast cancer , breast carcinoma , axillary lymphadenopathy , carcinoma , biopsy , cancer
Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins. Fine needle aspiration cytology was positive for duct carcinoma cells. Histo pathologic examination, reported as "Multicentric infiltrating duct carcinoma with squamous differentiation left breast", grade 2. Immunohistochemistry revealed negativity for ER, PR and positivity for HER-2/neu. We are presenting this rare case for clinical, radiological, histopathological and immunohistochemical study.