Open AccessAssociation of 8q24.21 rs10505477-rs6983267 Haplotype and Age at Diagnosis of Colorectal Cancer
Author(s) -
Monir Sadat Haerian,
Batoul Sadat Haerian,
Hassan Rooki,
Saadat Molanaei,
Farid Kosari,
Maedeh Obohhat,
Parisa Hosseinpour,
Pedram Azimzadeh,
Seyed Reza Mohebbi,
Zahra Akbari,
Mohammad Reza Zali
Publication year - 2014
Publication title -
asian pacific journal of cancer prevention
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 75
eISSN - 2476-762X
pISSN - 1513-7368
DOI - 10.7314/apjcp.2014.15.1.369
Subject(s) - haplotype , colorectal cancer , genotype , oncology , medicine , allele , population , genetics , cancer , biology , gene , environmental health
Colorectal cancer (CRC) is the fourth most common cause of cancer death in the world. Genetic variants in 8q24.21 including rs10505477 and rs6983267 have been hypothesized to be involved in susceptibility to CRC. This study aims to investigate the possible association between these loci and their haplotypes with CRC risk in Iranian population.