
Common variable immunodeficiency disorders: What generalists should know
Author(s) -
A C Jeevarathnum,
André Van Niekerk,
J Kriel,
R J Green
Publication year - 2021
Publication title -
african journal of thoracic and critical care medicine
Language(s) - English
Resource type - Journals
eISSN - 2617-0205
pISSN - 2617-0191
DOI - 10.7196/ajtccm.2021.v27i3.228
Subject(s) - common variable immunodeficiency , primary immunodeficiency , immune system , immunology , medicine , immunodeficiency , antibody , immunologic deficiency syndromes
Primary immune deficiency disorders (PIDDs) are common and underdiagnosed. Predominant antibody deficiencies (PADs) are the most common type of immune deficiency and comprise 55% of the immune deficiencies diagnosed. [1] Although immunoglobulin A (IgA) deficiency remains the most common type of PID, common variable immunodeficiency disorders remain the most common symptomatic PID for which medical therapy is sought.