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EVALUATION OF SUBCUTANEOUS CALCIUM HEPARIN THERAPY IN THE TREATMENT OF THROMBO‐EMBOLIC DISEASE
Author(s) -
Hirsh J.,
O'Sullivan E. F.,
Gallus A. S.,
Martin M.
Publication year - 1970
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1970.tb77688.x
Subject(s) - medicine , heparin , subcutaneous injection , anticoagulant therapy , calcium , anticoagulant , surgery , clotting time , anesthesia , thromboembolic disease , coagulation , thrombosis
Forty‐three patients were treated with calcium heparin by subcutaneous injection, and the anticoagulant response was carefully evaluated by serial clotting time determinations in 32 cases. An adequate anticoagulant effect could be obtained in the majority of patients with two injections per day, and in the remainder by either one or three injections per day. The drug was well tolerated, the only side effect being a mild allergic reaction at the site of injection in six patients. Treatment with subcutaneous calcium heparin injections appears to be safe and effective and should prove useful in the treatment of thrombo‐embolic disorders.