Open AccessClinical Implications of Functional Mitral Regurgitation Severity in Patients with Heart Failure with Reduced Ejection Fraction (HFrEF)
Author(s) -
Nabil Naser
Publication year - 2022
Publication title -
medicinski arhiv
Language(s) - English
Resource type - Journals
eISSN - 1986-5961
pISSN - 0350-199X
DOI - 10.5455/medarh.2022.76.17-22
Subject(s) - ejection fraction , heart failure , cardiology , medicine , mitral regurgitation , transthoracic echocardiogram , valvular heart disease , functional mitral regurgitation , physical examination , stroke volume
An estimated 64.3 million people are living with heart failure worldwide. Functional MR in chronic HFrEF reflects primarily the severity of LV dysfunction and is not related to structural alterations of the mitral valvular apparatus. FMR in patients with HFrEF independently of the etiology of HFrEF and its underlying mechanisms, contributes to progression of the symptoms of HF and is independent predictor of worse clinical outcomes.