Open AccessClinical, Neurophysiological and Histopatological correlations in Pure Neural Leprosy
Author(s) -
Izabela Jardim Rodrigues Pitta,
Bruno Siqueira Mietto,
Aron dos Santos Camilo,
Sérgio Luiz Gomes Antunes,
Euzenir Nunes Sarno,
Márcia Rodrigues Jardim
Publication year - 2021
Publication title -
brazilian journal of case reports
Language(s) - English
Resource type - Journals
ISSN - 2763-583X
DOI - 10.52600/2763-583x.bjcr.2021.1.4.105-113
Subject(s) - leprosy , medicine , nerve conduction , nerve biopsy , ulnar nerve , dermatology , skin biopsy , neurophysiology , biopsy , physical medicine and rehabilitation , neuroscience , peripheral neuropathy , pathology , surgery , psychology , psychiatry , elbow , endocrinology , diabetes mellitus
Although neuropathy remains one of the most problematic issues faced by leprosy patients, the evolving process of its findings continues a challenge particularly in pure neural leprosy (PNL). We evaluated neurological examination, nerve conduction studies and histhopathological data of patients with PNL and ulnar neuropathy. Patients with longer duration of symptoms had reduction in the motor conduction velocities and patients with fibrosis in the biopsy had axonal damage in the nerve conduction studies. This suggests that focal demyelination may be present in leprosy patients at the moment of the diagnosis and be related to the duration of the neuropathy.