Open AccessRetinoic Acid Correlates with Reduced Serum IL-10 And TGF-β in Allergic Rhinitis
Author(s) -
Akram Davoodi,
Ramin Lotfi,
Seyed Hamidreza Mortazavi,
Ali Gorgin Karaji,
Alireza Rezaiemanesh,
Farhad Salari
Publication year - 2021
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.467
H-Index - 8
ISSN - 2322-3480
DOI - 10.52547/rbmb.9.4.399
Subject(s) - retinoic acid , foxp3 , saliva , medicine , immunoglobulin e , immunology , transforming growth factor , cytokine , allergy , endocrinology , immune system , antibody , biology , gene , biochemistry
Retinoic acid (RA) plays a key role in naïve T cell differentiation into FOXP3+ Treg cell in the respiratory airways. The present study aims to investigate RA and Treg-related cytokine serum levels, salivary IgA levels, FOXP3 and IL-4 gene expression, and the relationships between RA serum levels and Treg-related cytokines in allergic rhinitis (AR) patients and healthy controls.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom