Open AccessMULTIPLE INFLAMMATORY SYNDROME IN CHILDREN (MIS-C) ASSOCIATED WITH COVID-19
Author(s) -
TINATIN KUTUBIDZE,
M Kherkheulidze,
Manana Kobakhidze,
Irine Kekelidze,
Eka Nakhutsrishvili
Publication year - 2021
Publication title -
ek'sperimentuli da klinikuri medic'ina
Language(s) - English
Resource type - Journals
ISSN - 1512-0392
DOI - 10.52340/jecmj.2021.378
Subject(s) - cytokine storm , medicine , covid-19 , systemic inflammatory response syndrome , disease , intensive care , cytokine , inflammation , infectious disease (medical specialty) , inflammatory response , intensive care medicine , pediatrics , immunology , pathology , sepsis , outbreak
There is a difference between MIS-C and KD. This is probably a postinfectious inflammatory response manifested with elevation of inflammatory markers and signs of myocardial damage. So, MIS-C could be an analogue of late phase COVID-19, which we are seeing in adult patients. This phase is also characterized by “cytokine storm” and can include severe myocardial disfunction, renal damage and laboratory changes consistent with MAS. Despite growing numbers of children with MIS-C, it still remains as rare condition and has good outcome in majority of cases. Children with MIS-C need special care of rheumatologist, infectious disease and intensive disease specialist collaboration.