Open AccessInvestigation of Thiol/Disulfide Balance in Obese Rats with Non-Alcoholic Fatty Liver Disease
Author(s) -
Serkan Tursun,
Hacer Fulya Gülerman,
Serkal Gazyağcı,
Yusuf Şahin,
Özcan Erel,
Salim Neşeli̇oğlu
Publication year - 2021
Publication title -
pediatric gastroenterology, hepatology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.44
H-Index - 19
eISSN - 2234-8646
pISSN - 2234-8840
DOI - 10.5223/pghn.2021.24.5.443
Subject(s) - fatty liver , medicine , oxidative stress , endocrinology , aspartate transaminase , steatosis , alanine transaminase , transaminase , homeostasis , thiol , chemistry , disease , biochemistry , enzyme , alkaline phosphatase
Due to the increasing prevalence of obesity worldwide, non-alcoholic fatty liver disease (NAFLD) has reached epidemic dimensions over time. NAFLD is the most common cause of childhood chronic liver disease. There is a relationship between NAFLD and oxidative stress. This study aims to investigate the changes in thiol/disulfide homeostasis parameters to determine the oxidant/antioxidant balance in obese rats with diet-induced NAFLD and healthy rats.